Circular RNA In Vitro Synthesis

As a new generation of therapeutic mRNAs, circRNAs may address some of the limitations of linear mRNA including increased stability, reduced immunogenicity, and tissue/cell-specific translation. Therefore, translatable circRNAs are able to produce more therapeutic protein inside the body than conventional mRNA, with the potential to engineer cells, replace damaged proteins, or add new beneficial proteins for patients with serious diseases.

IntegrateRNA has focused on the system development and optimization of circular RNA in vitro synthesis for several years, and has established excellent synthesis platforms for RNA drug discovery. We utilize the T4 DNA/RNA ligase circularization system and CBITR circularization system to provide customized circular RNA products in research-grade and pharmaceutical-grade. You can submit your target RNA sequence for a free consultation and project evaluation.